Selenophene-3-carbonitrile finds its primary application in the field of organic electronics, particularly in the development of semiconducting materials. Its unique electronic properties make it a valuable component in the synthesis of conjugated polymers and small molecules used in organic photovoltaic (OPV) devices. These materials are essential for improving the efficiency of solar cells by enhancing light absorption and charge transport.

Additionally, it is utilized in the fabrication of organic field-effect transistors (OFETs), where it contributes to the development of high-performance, flexible electronic devices. Its incorporation into the active layer of these transistors helps achieve better electrical conductivity and stability.

In medicinal chemistry, Selenophene-3-carbonitrile serves as a building block for the synthesis of bioactive compounds. Its structure is often modified to create potential drug candidates, particularly in the development of anticancer and antimicrobial agents. The presence of the selenophene ring and nitrile group allows for diverse chemical modifications, enabling the exploration of new therapeutic pathways.

Furthermore, it is employed in materials science for the creation of advanced coatings and sensors. Its ability to interact with various analytes makes it suitable for designing chemical sensors that detect specific substances with high sensitivity and selectivity.