1,8-Octanedithiol is primarily used in the field of nanotechnology and material science. It serves as a key chemical for creating self-assembled monolayers (SAMs) on gold and other metal surfaces. These SAMs are crucial for modifying surface properties, such as wettability, adhesion, and corrosion resistance, making it valuable in sensor development and protective coatings. Additionally, it is employed in the synthesis of organic-inorganic hybrid materials and as a crosslinking agent in polymer chemistry, enhancing the mechanical and thermal stability of materials. Its ability to form strong bonds with metal surfaces also makes it useful in the fabrication of nanoscale devices and electronic components.