6-Mercaptohexanoic acid is widely used in the field of surface modification and nanotechnology. It serves as a key component in the functionalization of gold nanoparticles, where its thiol group binds strongly to the gold surface, while the carboxylic acid group allows for further conjugation with biomolecules or polymers. This property makes it valuable in biosensing applications, enabling the detection of specific analytes with high sensitivity. Additionally, it is employed in the creation of self-assembled monolayers (SAMs) on metal surfaces, which are essential for studying interfacial phenomena and developing advanced materials with tailored properties. Its applications also extend to catalysis, where it acts as a stabilizing agent for metal nanoparticles, enhancing their performance in various chemical reactions.