LY 222306 is primarily utilized in research settings, particularly in the study of neurological and psychiatric disorders. It functions as a potent and selective antagonist for certain serotonin receptors, making it valuable for investigating the role of these receptors in brain function and behavior. Researchers use it to explore potential therapeutic applications for conditions such as anxiety, depression, and schizophrenia. Additionally, it aids in understanding the mechanisms of serotonin signaling pathways, contributing to the development of novel pharmacological treatments. Its specificity and efficacy in targeting serotonin receptors make it a critical tool in neuroscience and drug discovery research.