SB-568849 is primarily utilized in the field of pharmaceutical research, where it serves as a selective antagonist for the 5-HT1B receptor. This receptor is implicated in various neurological and psychiatric conditions, making SB-568849 a valuable tool in studying the pathophysiology of disorders such as depression, anxiety, and migraine. Researchers employ this compound to better understand the role of serotonin signaling in the brain, particularly how modulating 5-HT1B receptor activity can influence mood, behavior, and pain perception. Additionally, SB-568849 is used in preclinical studies to evaluate potential therapeutic interventions, aiding in the development of novel drugs targeting serotonin-related pathways. Its specificity and efficacy in blocking the 5-HT1B receptor make it a critical component in advancing neuroscience and pharmacology research.