8-Chloro-11-fluoro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
97%
Reagent
Code: #129279
CAS Number
298220-99-2
blur_circular Chemical Specifications
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Molecular Information
Weight
330.83 g/mol
Formula
C₁₉H₂₀ClFN₂
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Registry Numbers
MDL Number
MFCD24386416
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Physical Properties
Melting Point
>192 °C(dec.)
Boiling Point
426.9±45.0 °C(Predicted)
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Storage & Handling
Density
1.27±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Inert Gas
description Product Description
Used in pharmaceutical research as a key intermediate for developing serotonin receptor modulators, particularly targeting 5-HT2A and 5-HT2C receptors. Its structure supports the design of central nervous system (CNS) agents, including potential antipsychotics and anti-obesity drugs. The fluorine and chlorine substitutions enhance metabolic stability and receptor selectivity, making it valuable in optimizing drug candidates for improved efficacy and safety profiles. Commonly employed in structure-activity relationship (SAR) studies to explore potency and binding affinity in novel psychotherapeutic compounds.
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