2-[4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl]ethanol
98%
Reagent
Code: #160868
CAS Number
109806-71-5
blur_circular Chemical Specifications
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Molecular Information
Weight
330.85 g/mol
Formula
C₁₉H₂₃ClN₂O
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used primarily as a key intermediate in the synthesis of second-generation antihistamines, such as Cetirizine and Levocetirizine, which are H1 receptor antagonists effective against allergic reactions with minimal sedative effects. The structure features a piperazine ring substituted with a (4-chlorophenyl)(phenyl)methyl group and an ethanol side chain, facilitating further modifications to enhance receptor selectivity and pharmacokinetic properties. It is also utilized in research for developing other piperazine-based therapeutics targeting histamine-mediated responses.
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