WAY-604655 is primarily used in neuroscience research as a potent and selective agonist for the 5-HT2C receptor subtype. Its main application lies in studying the role of serotonin signaling in behavioral and physiological processes, particularly those related to mood regulation, appetite control, and reward pathways. Due to its selectivity, it is a valuable tool in differentiating 5-HT2C receptor-mediated effects from those of other serotonin receptor subtypes, such as 5-HT2A or 5-HT2B, which helps avoid confounding results in pharmacological studies. It has been employed in preclinical models to investigate potential treatments for psychiatric disorders, including depression, anxiety, and substance use disorders. Additionally, WAY-604655 has been used to explore the mechanisms underlying obesity and metabolic regulation, as activation of 5-HT2C receptors is known to reduce food intake and promote satiety. Its use remains restricted to laboratory and experimental settings, with no current clinical applications approved in humans.