WAY-322545 is primarily used in neuroscience research as a potent and selective antagonist for the 5-HT6 receptor subtype. Its main application lies in studying the role of serotonin signaling in cognitive functions, particularly in models related to learning and memory. Due to its high selectivity, it is employed to investigate potential therapeutic pathways for neurodegenerative disorders such as Alzheimer's disease. Researchers use WAY-322545 to modulate 5-HT6 receptor activity in preclinical models, helping to clarify the receptor's involvement in behavioral and cognitive processes. It is not used clinically but serves as a valuable pharmacological tool in central nervous system drug development.