WAY-325438 is a potent and selective antagonist of the 5-HT6 receptor, primarily used in neuroscience research to study cognitive function and neurodegenerative disorders. It has shown potential in improving learning and memory in preclinical models, making it a compound of interest in the development of treatments for Alzheimer's disease and other cognitive impairments. Due to its ability to modulate serotonin signaling without significant off-target activity, it serves as a valuable tool for investigating the role of 5-HT6 receptors in mood, appetite, and behavioral regulation. Its application remains largely confined to experimental settings, supporting drug discovery and mechanistic studies in central nervous system disorders.