WAY-640414 is primarily used in scientific research as a potent and selective antagonist for the 5-HT6 (serotonin 6) receptor. Its main application lies in neuroscience studies, particularly in investigating cognitive functions, memory processes, and potential treatments for neurodegenerative disorders such as Alzheimer's disease. Due to its ability to modulate serotonin signaling, it has been utilized in preclinical models to assess effects on learning, memory enhancement, and behavioral responses. It also serves as a pharmacological tool to help elucidate the role of 5-HT6 receptors in psychiatric conditions like schizophrenia and depression. Its high selectivity makes it valuable for target validation in drug discovery programs focused on central nervous system disorders.