WAY-638178-A is primarily used in scientific research for its potent and selective antagonistic activity at the 5-HT6 receptor. This makes it a valuable tool compound in neuroscience studies focused on cognitive function, memory, and neurodegenerative disorders such as Alzheimer's disease. It has been utilized in preclinical models to investigate the role of serotonin signaling in learning and behavior. Due to its high selectivity, it helps researchers isolate the effects of 5-HT6 receptor modulation without significant off-target interactions. Its application is mainly restricted to in vitro and in vivo research settings, aiding in the development of novel therapeutics targeting central nervous system disorders.