WAY-321364 is primarily used in scientific research as a selective antagonist for the 5-HT6 receptor, making it a valuable tool for studying serotonin signaling pathways in the central nervous system. It has been investigated for its potential to modulate cognitive functions, particularly in models of neurodegenerative diseases such as Alzheimer's. Due to its ability to cross the blood-brain barrier and influence neurotransmitter systems involved in learning and memory, WAY-321364 has served as a pharmacological probe to explore the role of 5-HT6 receptors in behavior, cognition, and psychiatric disorders. Its application remains confined to preclinical research, where it helps validate the therapeutic potential of 5-HT6 receptor modulation in treating cognitive impairments.