WAY-296818 is primarily used in scientific research to investigate the role of serotonin receptors, particularly the 5-HT6 receptor subtype, in cognitive and neurological functions. It acts as a potent and selective antagonist at these receptors, making it a valuable tool for studying conditions such as Alzheimer's disease, schizophrenia, and other disorders involving cognitive impairment. Researchers use WAY-296818 to explore how modulation of 5-HT6 activity affects memory, learning, and behavior in preclinical models. Its selectivity helps isolate receptor-specific effects, supporting the development of novel therapeutics targeting central nervous system disorders. Due to its research-focused profile, it is not used clinically but remains important in pharmacological studies aiming to validate new drug targets.