WAY-326100 is primarily used in scientific research as a potent and selective antagonist for the 5-HT6 (serotonin 6) receptor. Its main application lies in neuroscience studies, particularly in investigating the role of 5-HT6 receptors in cognitive function, memory, and neurodegenerative disorders such as Alzheimer's disease. Researchers use WAY-326100 to modulate serotonin signaling in the brain, helping to clarify the receptor's involvement in learning and memory processes. Due to its high selectivity, it is valuable in pharmacological assays and in vivo studies aimed at validating 5-HT6 as a therapeutic target for cognitive enhancement and psychiatric conditions. It is not used clinically and remains restricted to preclinical research.