PRE-084 hydrochloride is primarily used in research settings to study sigma-1 receptors, which are involved in various physiological processes. It acts as a selective agonist for these receptors, making it a valuable tool for investigating their role in neuroprotection, modulation of ion channels, and cellular signaling pathways. This compound is particularly useful in studies related to neurodegenerative diseases, such as Alzheimer's and Parkinson's, as well as in exploring its potential effects on pain management and psychiatric disorders. Additionally, PRE-084 hydrochloride is employed in preclinical research to understand its impact on cellular stress responses and its potential therapeutic applications in conditions like stroke and depression.