PK11007 is primarily utilized in research settings as a selective antagonist for the sigma-2 receptor. This receptor is of significant interest in the study of cancer biology, as it is often overexpressed in tumor cells. By targeting the sigma-2 receptor, PK11007 helps researchers investigate mechanisms of cell proliferation, apoptosis, and tumor growth inhibition. Its application extends to the development of potential cancer therapies, particularly in understanding how sigma-2 receptor modulation can influence tumor behavior. Additionally, PK11007 is used in neuropharmacology studies to explore its role in neurological disorders, where sigma receptors are implicated in disease pathology. Its selective binding properties make it a valuable tool for elucidating the complex roles of sigma-2 receptors in both cancer and neurological research.