β-D-Glucan from barley is widely used in the food and beverage industry as a dietary fiber additive to enhance the nutritional profile of products. It is incorporated into baked goods, cereals, and beverages to improve texture, moisture retention, shelf life, and blood sugar control. In the health and wellness sector, it is utilized as a functional ingredient in supplements due to its ability to support immune function, promote cardiovascular health by reducing cholesterol levels, and provide antioxidant properties. Additionally, it is employed in skincare products for its moisturizing, soothing, and antioxidant effects, helping to improve skin barrier function, reduce irritation, and nourish the skin. Its biocompatibility and bioactive properties also make it a candidate for research in biomedical applications, such as wound healing and drug delivery systems.