tert-Butyl 6-bromospiro[chromane-2,4'-piperidine]-1'-carboxylate
97%
Reagent
Code: #150823
CAS Number
1194374-64-5
blur_circular Chemical Specifications
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Molecular Information
Weight
382.29 g/mol
Formula
C₁₈H₂₄BrNO₃
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Registry Numbers
MDL Number
MFCD11227132
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of central nervous system agents. Its spirocyclic structure and functional groups make it valuable for constructing complex piperidine-based drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship studies due to the stability imparted by the tert-butoxycarbonyl (Boc) protecting group. The bromine atom allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig, enabling rapid diversification in lead optimization. Also utilized in the preparation of selective enzyme inhibitors and receptor modulators.
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