tert-Butyl 7-bromo-3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate
≥95%
Reagent
Code: #151189
CAS Number
1160247-52-8
blur_circular Chemical Specifications
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Molecular Information
Weight
380.28 g/mol
Formula
C₁₈H₂₂BrNO₃
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Registry Numbers
MDL Number
MFCD12198608
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Storage & Handling
Storage
Room temperature, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its spirocyclic structure and functional groups make it valuable for constructing complex piperidine-based scaffolds found in bioactive molecules. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies, especially in the design of receptor modulators. The bromo substituent allows for further functionalization via cross-coupling reactions, enabling rapid diversification in drug discovery programs. Also utilized in the preparation of selective enzyme inhibitors and neuroactive agents due to its conformational rigidity and favorable pharmacokinetic properties.
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