tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
97%
Reagent
Code: #153067
CAS Number
2089301-60-8
blur_circular Chemical Specifications
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Molecular Information
Weight
347.37 g/mol
Formula
C₁₇H₂₁N₃O₅
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules. Its spirocyclic structure provides conformational rigidity, enhancing selectivity and metabolic stability in drug candidates. The nitro group allows for further functionalization, enabling the construction of complex heterocyclic systems. The Boc-protected piperidine moiety facilitates peptide-like coupling and deprotection strategies in multi-step syntheses. Commonly employed in medicinal chemistry for optimizing lead compounds targeting central nervous system disorders and oncology pathways.
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