Spiro[2.2]pentane-1-carboxylic acid finds its primary application in organic synthesis, particularly as a building block for creating complex molecular structures. Its unique spirocyclic framework is valuable in the development of pharmaceuticals, where it can impart specific conformational properties to drug molecules, enhancing their binding affinity or stability. Additionally, it is used in materials science to design novel polymers or small molecules with tailored physical or chemical properties. The compound’s rigid structure also makes it a useful intermediate in the synthesis of fine chemicals and specialty compounds.