Widely used in biochemical and metabolic research to study estrogen metabolism and detoxification pathways in the liver. Serves as a reference standard in analytical methods like HPLC and mass spectrometry for identifying estrogen conjugates in biological samples. Applied in endocrinology to understand hormone transport and excretion, as this glucuronidated form is a major metabolite excreted in urine and bile. Also utilized in studies assessing drug interactions with hormone-processing enzymes such as UDP-glucuronosyltransferases (UGTs).