Trans-4-Nitrostilbene is primarily used in the field of organic synthesis and materials science. It serves as a key intermediate in the production of various organic compounds, particularly those involving stilbene derivatives. Its application extends to the development of fluorescent dyes and optical brighteners, where its structural properties enhance light absorption and emission characteristics. Additionally, it is utilized in the study of photochemical reactions due to its ability to undergo photo-isomerization, making it valuable in research related to light-responsive materials. In the pharmaceutical industry, it is explored for its potential in the synthesis of bioactive molecules, contributing to the development of new therapeutic agents.