4,4'-Dimethyl-trans-stilbene is primarily used in organic synthesis and materials science. It serves as a key intermediate in the production of various organic compounds, particularly those involving stilbene derivatives. Its structural properties make it valuable in the development of fluorescent dyes and optical brighteners, which are widely used in textiles, paper, and detergents to enhance brightness and whiteness. Additionally, this compound is studied for its potential applications in liquid crystal displays (LCDs) due to its ability to influence molecular alignment and stability. In research, it is also utilized as a model compound to study photochemical reactions and polymerization processes, contributing to advancements in polymer chemistry and photonics.