3-((tert-Butyldimethylsilyl)oxy)azetidine
96%
Reagent
Code: #130584
CAS Number
875340-81-1
blur_circular Chemical Specifications
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Molecular Information
Weight
187.35 g/mol
Formula
C₉H₂₁NOSi
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Registry Numbers
MDL Number
MFCD20662828
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Physical Properties
Boiling Point
192.2±33.0 °C(Predicted)
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Storage & Handling
Density
0.89±0.1 g/cm3(Predicted)
Storage
2-8°C, away from light, dry
description Product Description
Used as a protected intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and biologically active compounds. The silyl ether group provides stability to the hydroxyl functionality while allowing selective deprotection under mild conditions, making it valuable in multi-step synthesis. Commonly employed in the development of kinase inhibitors and other medicinal agents where azetidine serves as a rigid scaffold. Its protected form enhances solubility and compatibility with various reaction conditions, including cross-coupling and nucleophilic substitution reactions.
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