1-(2,2,2-Trifluoroethyl)azetidin-3-ol

98%

Reagent Code: #132741
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CAS Number 1344365-71-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 155.12 g/mol
Formula C₅H₈F₃NO
badge Registry Numbers
MDL Number MFCD18309092
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals. The structure features an azetidine ring substituted with a 2,2,2-trifluoroethyl group at position 1 and a hydroxyl group at position 3, supporting the development of enzyme inhibitors and receptor modulators. The trifluoroethyl moiety enhances lipophilicity, metabolic stability, and membrane permeability, while the hydroxyl and azetidine groups enable hydrogen bonding and structural rigidity, improving binding affinity in drug molecules. Commonly applied in medicinal chemistry for optimizing pharmacokinetic properties such as solubility and bioavailability. Widely used in the design of fluorinated drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿15,150.00

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