Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. The nitroazetidine core serves as a versatile building block for developing novel drug candidates, especially those targeting central nervous system disorders and infectious diseases. The tert-butoxycarbonyl (Boc) protecting group allows for selective functionalization of the azetidine nitrogen, enabling controlled multi-step synthesis. Its strained four-membered ring structure imparts unique conformational properties useful in medicinal chemistry for modulating potency, metabolic stability, and bioavailability. Commonly employed in the preparation of protease inhibitors and receptor modulators where small ring systems enhance target binding selectivity.