tert-Butyl3-(4-Methoxybenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)azetidine-1-carboxylate
≥98%(GC)(T)
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description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. Its boronate ester group facilitates carbon-carbon bond formation under mild conditions, making it valuable for constructing biaryl and heterobiaryl systems. The 4-methoxybenzyl substituent at the 3-position enhances solubility in organic solvents and supports compatibility in multi-step syntheses. The tert-butyloxycarbonyl (Boc) protecting group on the azetidine ring allows for selective deprotection and further functionalization, supporting its use in multi-step synthesis of bioactive compounds. Commonly applied in medicinal chemistry for developing drug candidates with azetidine scaffolds, known for improved metabolic stability and favorable physicochemical properties.
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