2-Bromo-3-Methylpyridine 1-Oxide
95%
science Other reagents with same CAS 19230-57-0
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description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of nicotinic receptor agonists and antagonists. It serves as a building block in the preparation of bioactive molecules due to the presence of both bromine and the pyridine N-oxide functionality, which allow for selective functionalization through cross-coupling reactions and directed ortho-metalation. Commonly employed in agrochemical research for designing novel pesticides and in medicinal chemistry for constructing complex heterocyclic systems. The N-oxide group enhances solubility and can act as a directing group in metal-catalyzed reactions, improving regioselectivity during derivatization.
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