Used primarily as a highly reactive sulfonylating agent in organic synthesis, particularly in the preparation of sulfonate esters and sulfonamides. Its fluoride leaving group enhances reactivity under mild conditions, making it suitable for late-stage functionalization in pharmaceutical and agrochemical development. It is also employed in chemical biology for selective protein labeling and inhibitor design due to its ability to react with nucleophilic amino acid residues. Handles with care due to its lachrymatory and moisture-sensitive properties.