3,4-Difluorobenzenesulfonyl fluoride
95%
Reagent
Code: #167373
CAS Number
115561-01-8
blur_circular Chemical Specifications
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Molecular Information
Weight
196.15 g/mol
Formula
C₆H₃F₃O₂S
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Registry Numbers
MDL Number
MFCD21882105
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Physical Properties
Boiling Point
72 °C
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Storage & Handling
Density
1.525±0.06 g/cm3(Predicted)
Storage
Room temperature, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules and enzyme inhibitors. Its sulfonyl fluoride group readily reacts with nucleophiles, making it valuable in medicinal chemistry for constructing sulfonamide linkages. It is also employed in chemical biology as a labeling agent due to its ability to selectively modify proteins and other biomolecules. The presence of fluorine atoms enhances binding affinity and metabolic stability in drug candidates, contributing to improved pharmacokinetic properties. Additionally, it serves as a building block in agrochemicals and functional materials where fluorinated aromatic systems are advantageous.
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