Dextrin (USP/BP, For Direct Compression)

Food Code: 126096

commonly derived from starches, including maize or potato, and is used in pharmaceutical formulations for various purposes due to its versatility

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Dextrin (USP/BP, For Direct Compression)

commonly derived from starches, including maize or potato, and is used in pharmaceutical formulations for various purposes due to its versatility

Dextrin is a carbohydrate commonly derived from starches, including maize or potato, and is used in pharmaceutical formulations for various purposes due to its versatility. In drug formulations, dextrin serves several roles:

  1. Binder: Dextrin is often used as a binder in tablet formulations, helping hold the ingredients together, which improves the mechanical strength of tablets. It provides cohesion among particles, ensuring tablets do not crumble during production, packaging, or handling.

  2. Disintegrant: In some formulations, dextrin can act as a disintegrant, promoting the breakup of tablets in the digestive tract to facilitate faster release of the active ingredients. Its water solubility and slight swelling ability aid in this function.

  3. Filler or Diluent: Dextrin is also used as a filler in tablet and capsule formulations when the active ingredient has a low dosage. It adds bulk to the tablet, making it easier to handle and consume.

  4. Film-Coating Agent: Dextrin can be used as a component of film coatings for tablets. It helps protect the active ingredient from environmental factors (e.g., moisture, light) and can improve the appearance of tablets, making them easier to swallow.

  5. Carrier for Spray-Dried Powders: Due to its solubility and stability, dextrin is used as a carrier or encapsulating agent in spray-drying processes, especially for liquid or sensitive ingredients that need to be converted into a powder form.

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