Tariquidar methanesulfonate, hydrate
≥98%
Reagent
Code: #102789
CAS Number
625375-83-9
blur_circular Chemical Specifications
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Molecular Information
Weight
892.99 g/mol
Formula
C₄₀H₅₂N₄O₁₅S₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used primarily in medical research and clinical studies, this compound is investigated for its potential to reverse multidrug resistance in cancer treatments. It acts as an inhibitor of P-glycoprotein, a protein that cancer cells often overexpress to pump out chemotherapeutic drugs, thereby reducing their effectiveness. By blocking this protein, it aims to enhance the intracellular concentration of anticancer drugs, improving therapeutic outcomes. Studies are ongoing to evaluate its efficacy and safety when combined with other chemotherapy agents, particularly in resistant cancers like ovarian, lung, and breast cancer. Additionally, it is explored in preclinical models to understand its pharmacokinetics and pharmacodynamics better.
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