TIC-10 is primarily investigated for its potential in cancer therapy. It functions as an activator of the protein kinase ERK, which plays a crucial role in cell signaling pathways related to cell growth and survival. By modulating these pathways, TIC-10 has shown promise in inducing cancer cell death, particularly in resistant or aggressive tumor types. Its ability to cross the blood-brain barrier also makes it a candidate for treating brain cancers, such as glioblastoma. Additionally, TIC-10 has been studied for its potential to enhance the efficacy of other chemotherapeutic agents, offering a synergistic approach to cancer treatment. Research continues to explore its safety, dosing, and broader applications in oncology.