Desmorpholinyl Navitoclax-NH-Me
≥98%
Reagent
Code: #106169
CAS Number
2365172-82-1
blur_circular Chemical Specifications
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Molecular Information
Weight
918.55 g/mol
Formula
C₄₄H₅₁ClF₃N₅O₅S₃
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Desmorpholinyl Navitoclax-NH-Me is primarily utilized in the field of cancer research and therapy. It is a modified version of Navitoclax, designed to enhance its efficacy and specificity in targeting cancer cells. This compound is particularly effective in inhibiting the BCL-2 family of proteins, which play a crucial role in the survival and resistance of cancer cells to apoptosis. By disrupting these proteins, it promotes programmed cell death in malignant cells, making it a valuable tool in the treatment of various cancers, including hematologic malignancies and solid tumors. Additionally, its modified structure aims to improve pharmacokinetic properties, such as bioavailability and stability, thereby enhancing its therapeutic potential in clinical settings. Researchers are also exploring its use in combination therapies to overcome drug resistance and improve overall treatment outcomes.
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