MRTX849 acid
≥98%
Reagent
Code: #106306
CAS Number
2561529-96-0
blur_circular Chemical Specifications
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Molecular Information
Weight
662.15 g/mol
Formula
C₃₄H₃₇ClFN₇O₄
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Storage & Handling
Storage
2-8°C, protected from light, dry, sealed
description Product Description
MRTX849 acid is primarily utilized in the development of targeted cancer therapies. It functions as a potent and selective inhibitor of KRAS G12C, a specific mutation found in various cancers, including non-small cell lung cancer (NSCLC) and colorectal cancer. By binding to the mutated KRAS protein, it effectively blocks its activity, inhibiting tumor growth and proliferation. This makes it a promising candidate for precision medicine, particularly for patients with KRAS G12C-mutated cancers who have limited treatment options. Its application is currently being explored in clinical trials to assess its efficacy, safety, and potential as a standalone or combination therapy in oncology.
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