β-Amanitin

98%

Reagent Code: #110045
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CAS Number 21150-22-1

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scatter_plot Molecular Information
Weight 920 g/mol
Formula C₃₉H₅₃N₉O₁₅S
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

description Product Description

β-Amanitin is primarily used in scientific research to study the mechanisms of RNA polymerase II inhibition. It is a potent toxin that selectively binds to and inhibits this enzyme, making it a valuable tool for understanding transcription processes in eukaryotic cells. Researchers utilize it to investigate cell death pathways, particularly apoptosis, and to explore the effects of transcriptional arrest on cellular functions. Additionally, β-Amanitin is employed in the development of targeted therapies, such as antibody-drug conjugates, where its toxic properties are harnessed to selectively destroy cancer cells. Its application in molecular biology and toxicology has provided critical insights into gene expression regulation and cellular responses to stress.

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Test Parameter Specification
Appearance White To Off-White Powder
Purity (%) 97.5-100%
Infrared Spectrum Conforms To Structure
NMR Conforms To Structure

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿116,000.00
β-Amanitin
β-Amanitin is primarily used in scientific research to study the mechanisms of RNA polymerase II inhibition. It is a potent toxin that selectively binds to and inhibits this enzyme, making it a valuable tool for understanding transcription processes in eukaryotic cells. Researchers utilize it to investigate cell death pathways, particularly apoptosis, and to explore the effects of transcriptional arrest on cellular functions. Additionally, β-Amanitin is employed in the development of targeted therapies, such as antibody-drug conjugates, where its toxic properties are harnessed to selectively destroy cancer cells. Its application in molecular biology and toxicology has provided critical insights into gene expression regulation and cellular responses to stress.
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