Used in ophthalmology to treat age-related macular degeneration, diabetic macular edema, and macular edema following retinal vein occlusion by inhibiting vascular endothelial growth factor (VEGF), thereby reducing abnormal blood vessel growth and fluid leakage in the retina. Also utilized in oncology for metastatic colorectal cancer, where it acts as a VEGF trap to inhibit tumor angiogenesis and slow cancer progression. Administered via intravitreal injection for eye conditions and intravenous infusion in cancer therapy.