Used primarily in the treatment of cutaneous T-cell lymphoma (CTCL), particularly for patients with refractory or advanced stages of the disease. It functions as a retinoid X receptor (RXR) agonist, modulating gene expression involved in cell differentiation, proliferation, and apoptosis. Bexarotene helps reduce tumor burden and alleviate skin manifestations associated with CTCL. It is also investigated for potential use in other cancers and neurological conditions like Alzheimer’s disease due to its role in regulating lipid metabolism and amyloid clearance, though these applications remain experimental.