ABBV-744
99%
Reagent
Code: #99348
CAS Number
2138861-99-9
blur_circular Chemical Specifications
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Molecular Information
Weight
491.55 g/mol
Formula
C₂₈H₃₀FN₃O₄
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Storage & Handling
Storage
-20℃
description Product Description
ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | powder |
Purity | 98.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
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ABBV-744
ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.
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