ABBV-744

99%

Reagent Code: #99348
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CAS Number 2138861-99-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 491.55 g/mol
Formula C₂₈H₃₀FN₃O₄
inventory_2 Storage & Handling
Storage -20℃

description Product Description

ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.

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Test Parameter Specification
Appearance powder
Purity 98.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿16,200.00
inventory 10mg
10-20 days ฿24,710.00
inventory 1mg
10-20 days ฿6,800.00
ABBV-744
ABBV-744 is primarily utilized in the field of oncology, specifically targeting cancers that are driven by the overexpression of BET proteins. It functions as a selective inhibitor of the BD2 domain within BET proteins, which plays a crucial role in regulating gene expression related to cancer cell growth and survival. This selectivity allows ABBV-744 to potentially reduce off-target effects compared to pan-BET inhibitors, making it a promising candidate for treating hematologic malignancies such as acute myeloid leukemia (AML) and multiple myeloma. Its application is currently under investigation in clinical trials to assess its efficacy and safety in patients with these types of cancers.
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