AMD 3465 is primarily used in research and pharmaceutical applications due to its role as a CXCR4 chemokine receptor antagonist. It is extensively studied for its potential in cancer therapy, particularly in inhibiting the CXCR4 receptor, which is often overexpressed in various cancer types. By blocking this receptor, it can prevent cancer cell migration, metastasis, and tumor growth. Additionally, it is explored in the context of HIV research, as the CXCR4 receptor is a co-receptor for certain strains of the virus, making AMD 3465 a candidate for antiviral strategies. It is also investigated for its potential in stem cell mobilization, aiding in the collection of hematopoietic stem cells for transplantation.