AV-412 free base is primarily utilized in the field of medical research, particularly in the study of cancer therapies. It functions as an inhibitor targeting specific tyrosine kinases, which are enzymes that play a crucial role in the signaling pathways of cancer cells. By inhibiting these kinases, AV-412 free base helps in disrupting the growth and proliferation of tumor cells. This makes it a valuable compound in preclinical studies aimed at developing new anticancer drugs. Researchers also explore its potential in combination therapies, where it may enhance the efficacy of other chemotherapeutic agents. Additionally, its mechanism of action is studied to understand resistance mechanisms in cancer cells, providing insights for overcoming treatment challenges.