AZD5153 is primarily used in the field of cancer research and treatment. It functions as a potent and selective inhibitor of BRD4, a protein that plays a critical role in regulating gene expression, particularly in cancer cells. By inhibiting BRD4, AZD5153 disrupts the expression of genes that drive cancer cell growth and survival, making it a promising candidate for targeted cancer therapies. It is being studied for its potential in treating various cancers, including hematologic malignancies and solid tumors. Additionally, AZD5153 is utilized in preclinical studies to better understand the mechanisms of BRD4 and its role in oncogenesis, aiding in the development of novel therapeutic strategies.