E3 ligase Ligand 15

97%

Reagent Code: #106182
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CAS Number 2306390-08-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 639.53 g/mol
Formula C₃₂H₃₂Cl₂N₄O₆
badge Registry Numbers
MDL Number MFCD32197284
inventory_2 Storage & Handling
Storage 2-8°C, dry, sealed

description Product Description

Primarily utilized in the field of targeted protein degradation, this compound plays a crucial role in the development of PROTACs (Proteolysis Targeting Chimeras). It functions by recruiting E3 ubiquitin ligases to specific proteins of interest, facilitating their ubiquitination and subsequent degradation by the proteasome. This mechanism is particularly valuable in drug discovery and therapeutic research, especially for targeting proteins that are traditionally considered "undruggable." Its application extends to cancer research, where it helps in degrading oncogenic proteins, and in neurodegenerative disease studies, where it aids in eliminating misfolded or aggregated proteins. Additionally, it is employed in chemical biology to study protein function and interactions, providing insights into cellular pathways and disease mechanisms.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿42,750.00

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