Cuparene is primarily used in the fragrance and flavor industry due to its woody, earthy, and slightly sweet aroma. It serves as a key component in perfumery, especially in creating base notes for woody and oriental scents. Its stability and tenacity make it valuable in enhancing the longevity of perfumes in cosmetics and personal care products. Additionally, cuparene is used in aromatherapy formulations and scented household products such as candles, soaps, and air fresheners to impart a natural, forest-like scent. It also finds use as a reference compound in chemical research involving sesquiterpenes and in studies of biosynthetic pathways in plants.