Primarily used in organic synthesis, 5-Oxotetrahydrofuran-2-carboxylic acid serves as a key intermediate in the production of various pharmaceuticals and fine chemicals. It is particularly valuable in the synthesis of lactone derivatives, which are essential in creating bioactive compounds. Additionally, it finds application in the development of polymers and resins, where it contributes to enhancing material properties. Its role in synthesizing chiral molecules also makes it significant in asymmetric catalysis, aiding in the production of enantiomerically pure substances.