Methyltetrazine-PEG8-acid
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Methyltetrazine-PEG8-acid is widely used in bioconjugation and click chemistry applications due to its reactive tetrazine group and water-soluble PEG linker. It is particularly valuable in labeling biomolecules, such as proteins, antibodies, and peptides, for imaging, diagnostics, and drug delivery systems. The tetrazine moiety enables rapid and selective reactions with dienophiles like trans-cyclooctenes (TCOs) in bioorthogonal chemistry, making it ideal for live-cell imaging and in vivo studies. The PEG8 spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation. This compound is also employed in the development of targeted therapeutics, where precise attachment of payloads to biomolecules is required. Its versatility makes it a key tool in advanced biomedical research and therapeutic design.
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