Used as a highly reactive reagent in organic synthesis, particularly in the preparation of tetrazine derivatives for bioorthogonal chemistry. Its strong electron-deficient character makes it ideal for inverse electron-demand Diels-Alder reactions, which are widely applied in bioconjugation, labeling of biomolecules, and live-cell imaging. Also employed in materials science to construct nitrogen-rich heterocyclic systems for functional polymers and energetic materials.