tert-Butyl (4-bromo-5-formylthiazol-2-yl)carbamate

97%

Reagent Code: #146763
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CAS Number 944805-17-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 307.16 g/mol
Formula C₉H₁₁BrN₂O₃S
inventory_2 Storage & Handling
Storage 2-8°C, inert gas atmosphere

description Product Description

Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals targeting kinase inhibitors and antimicrobial agents. Its aldehyde group at the 5-position allows for further functionalization via reactions such as reductive amination or Wittig transformations, enabling the construction of complex heterocyclic systems. The 4-bromo substituent facilitates derivatization through cross-coupling reactions, such as Suzuki or Heck couplings, for introducing aryl or alkenyl groups. The tert-butyl carbamate (Boc) group provides protection for the amine during multi-step syntheses, ensuring selective reactivity. Commonly employed in medicinal chemistry for developing thiazole-based drug candidates due to the scaffold’s metabolic stability and favorable binding properties.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿580.00
inventory 250mg
10-20 days ฿1,870.00
inventory 1g
10-20 days ฿6,990.00
inventory 5g
10-20 days ฿34,400.00

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